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Dr. Gerald Rubin Collection: Model Organism Genome Sequencing, 1992-1999

Identifier: GR

Scope and Content

This collection is related to the development of a catalog for the Human Genome Project Archives. Of historical value is one of the three original signed documents dated January 1999 with Celera Genomics that spelled out the terms for the collaboration on the Drosophila genome sequencing project, signed by Craig Venter, founder of Celera Genomics in 1998, Gerald Rubin, and an official of the University of California at Berkeley. There also includes a folder on including emails and letters that deals with the Department of Energy’s consideration in 1992 of supporting model organisms sequencing. The question raised of whether is would be best to sequence worms or flies. There are letters from future Nobelists Robert Waterson and John Sulston praising the superiority of worms, and opposing views from Jasper Rine and Gerald Rubin promoting flies as the ideal model organism. Included are views from other scientists including Raymond Gesteland, and Lloyd Smith are included on this topic. There is also correspondence on DOE/NIH relations relevant to the Drosophila mapping project.


  • 1992-1999


Language of Materials

Bulk in English; .

Access Restrictions

Some restrictions apply, see Archivist for details. Access is given only by appointment, 8:00a.m. to 4:45p.m. Monday through Friday.

Use Restriction

Archival materials must remain in the archival reading area. Item duplication is to be done by archivists. Fees are applied to copies made. Digital photography is permitted by users. Due to the very fragile nature of some materials in this collection, some are available through photocopies; others must be used under the supervision of an archivist.


Gerald Rubin is also a professor of Genetics and Development at the University of California, Berkeley. He came to Cold Spring Harbor Laboratory as an URP (Undergraduate Research Program) in the early 70’s working under Lionel Crawford and Ray Gesteland before moving to Cambridge to earn his Ph.D. in molecular biology. He did postdoctoral work at Stanford University School of Medicine and became an assistant professor of biological chemistry at Harvard Medical School prior to commencing his genetics professorship at Berkeley in 1983. Currently, as Vice President and Director of the Janelia Farm Research Campus at the Howard Hughes Medical Institute in Ashburn, Virginia, his research focus is on developing the biological and computer tools that are capable of analyzing and displaying the vast amount of information available from the genomic DNA sequencing of the fruit fly. He uses these advanced techniques to decipher gene regulation and expression at a genome-wide level in Drosophila and determine the function of certain fruit fly genes..

Gerald Rubin is a member of the National Academy of Sciences and the Institute of Medicine. Among the awards he has received is the American Chemical Society Eli Lilly Award in biological chemistry.


2 Files


Dr. Gerald Rubin Collection: Model Organism Genome Sequencing, 1992-1999 contains documents pertinent to the collaboration on the Drosophila sequencing project in 1999, the agreement with Celera Genomics collaboration, emails and letters relating to the D.O.E. consideration of support for model organisms sequencing.

Arrangement Note

Materials were received directly from Dr. Rubin and kept in the original order.


This collection was donated by Gerald Rubin in December, 1999 from his personal collection. It was accessioned in January 2010, accession number 2010-109. The collection was processed in August 2012.

Related Collections

Related collections in the CSHL Library and Archives are the Norton Zinder Collection, the James D. Watson Collection, and the Sydney Brenner Collection.His interview can be found at Cold Spring Harbor Laboratory Oral History Office. Scholars should also refer to other institutions including Georgetown University, The National Human Genome Research Institute, the Smithsonian Institution, and the National Archives.

Dr. Gerald Rubin Collection: Model Organism Genome Sequencing, 1992-1999
Finding Aid Prepared by Clare Clark.
Language of description
Script of description
Code for undetermined script
Language of description note
Finding aid written in English.

Repository Details

Part of the Cold Spring Harbor Laboratory Archives Repository

Library & Archives
Cold Spring Harbor Laboratory
One Bungtown Rd
Cold Spring Harbor NY 11724 USA