Molecular Cytogenetics Bridging the Resolution Gap, 1989-10-30 - 1989-11-02
Scope and Contents
The meeting, Molecular Cytogenetics: Bridging the Resolution Gap, examined new strategies for handling and analyzing DNA intermediate in size between the DNAs studied by cytogenetics and by cloning techniques. It seems that although one can optimize techniques and strategies, a considerable element of luck is involved in finding a sought-after gene in kilobases of DNA.
Dates
- Creation: 1989-10-30 - 1989-11-02
Creator
- Allshire, Robin (Person)
- Ballabio, Andrea (Person)
- Brown, Stephen (Person)
- Bruns, Gail (Person)
- Burmeister, Margit (Person)
- Chakravarti, Aravinda (Person)
- Clarke, Louise (Person)
- Collins, Francis S. (Person)
- Cooke, Howard (Person)
- Davies, K. E. (Kay E.) (Person)
- Emanuel, Beverly (Person)
- Francke , Uta (Person)
- Goodfellow, Peter (Person)
- Graham, Bettie (Person)
- Groppi, Vince (Person)
- Hall, Judith (Person)
- Hassold, Terry (Person)
- Horsthemke, Bernhard (Person)
- Ledbetter, David (Person)
- Miller, Orlando (Person)
- Monaco, Anthony (Person)
- Nicholls, Robert (Person)
- Nussbaum, Robert (Person)
- Reik, Wolf (Person)
- Sapienza, Carmen (Person)
- Trask, Barbara (Person)
- Vogeli, Gabriel (Person)
- Ward, David (Person)
- Warren, Stephen (Person)
- Willard, Huntington (Person)
- Wong, Gordon (Person)
Conditions Governing Access
Tapes have been digitized and are available for research in person at CSHL Archives.
Extent
10 Cassettes : Tape 1 Side 1 [00:47:16] Tape 1 Side 2 [00:47:16]; Tape 2 Side 1 [00:47:17] Tape 2 Side 2 [00:45:18]; Tape 3 Side 1 [00:46:59] Tape 3 Side 2 [00:47:01]; Tape 4 Side 1 [00:46:57] Tape 4 Side 2 [00:46:58]; Tape 5 Side 1 [00:47:14] Tape 5 Side 2 [00:47:15]; Tape 6 Side 1 [00:47:03] Tape 6 Side 2 [00:47:04]; Tape 7 Side 1 [00:47:19] Tape 7 Side 2 [00:47:21]; Tape 8 Side 1 [00:47:04] Tape 8 Side 2 [00:47:05]; Tape 9 Side 1 [00:46:56] Tape 9 Side 2 [00:46:56]; Tape 10 Side 1 [00:46:58] Tape 10 Side 2 [00:28:54]
Language of Materials
From the Collection: English
Session 1: Bridging Technologies
High Resolution Gene Mapping by In Situ Hybridization / David Ward
Genomic Distance Estimated From the Proximity of Fluorescence In Situ Hybridization Sites in Interphase Nuclei / Barbara Trask
Microdissection and Molecular Analysis of Human Chromosome Regions Involved in Contiguous Syndromes / Bernhard Horsthemke
Physical Mapping and Microdissection in the Fragile X Region / Kay Davies
Human Genome Linking with Cosmids and Yeast Artificial Chromosomes / Anthony Monaco
Session 2: Chromosome Structure
Structure-Function Analysis of Centromeric DNA in Fission Yeast / Louise Clarke
Molecular Studies of X-inactivation / Huntington Willard
The Long Range Genetic and Physical Mapping of Mouse Chromosomes / Steve Brown
The Structure of the Pseudoautosomal Boundary / Peter Goodfellow
Discussion
Session 3: Reverse Genetic Cloning Strategies
Molecular and Cytogenetic Studies of 22q11 / Beverly Emanuel
Isolation of Human Xq28 Within a Somatic Cell Hybrid by Fragile Site-directed Rearrangement: Application to Saturational Cloning and Genome Analysis / Stephen Warren
Discussion
Session 4: Contiguous Gene Syndromes
Contiguous Gene Syndromes in the Distal Short Arm of the Human X-Chromosome / Andrea Ballabio
Identifying Human Genetic Disease by Map Position: Application of X-linked Opthalmological Disease / Robert Nussbaum
Organization of the WAGR Region / Gail Bruns
Molecular Dissection of the Miller-Dicker Lissenopholy Syndrome / David Ledbetter
Discussion
Session 5: Origin and Mechanism of Chromosome Abnormalities
Prader-Willi and Angelman Syndromes: Are Both Parental Contributions to Chromosome 15q11q13 Necessary for Normal Human Development? / Robert Nicholls
The Role of DNA Methylation in Mammalian Genome in Printing / Wolf Reik
Analysis of Non-Disjunction in Down's Syndrome and Ovarian Teratoma / Aravinda Chakravarti
Genetics of Genome Imprinting / Carmen Sapienza
Genomic Imprinting: Relecance for Human Diseases / Judith Hall
Repository Details
Part of the Cold Spring Harbor Laboratory Archives Repository
Library & Archives
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