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Fred Sanger, 2005-06-16

 Item — Box: AV03, miniDV: CSHL1147
Oral History | Frederick Sanger
Oral History | Frederick Sanger

Scope and Contents

Frederick Sanger, biochemist and a two time Nobel laureate, is interviewed by Mila Pollock, on June 16, 2005, at his home, Far Leys, in Cambridge, England.

Frederick Sanger discusses the following in his interview: Scene 1. Working with Albert Neuberger on amino acid metabolism -- Scene 2. Identifying amino groups in insulin -- Scene 3. Development of the field of protein chemistry -- Scene 4. A hands-on approach to biology -- Scene 5. Developing methods for determining nucleotide sequences -- Scene 6. The chain termination method: Sanger sequencing -- Scene 7. Sequencing phage ΦΧ174, 1982 -- Scene 8. Large-scale sequencing strategies: the Human Genome Project -- Scene 9. Reaction to the 2003 announcement of the completion of the Human Genome Project -- Scene 10. Since 1975: the dideoxy method for DNA sequencing -- Scene 11. Gene patenting -- Scene 12. Views on the dangers of genomic research -- Scene 13. Research at Cambridge University and the Medical Research Council's Laboratory of Molecular Biology -- Scene 14. Working with Francis Crick -- Scene 15. Influential colleagues -- Scene 16. Conducting an experiment with Sydney Brenner -- Scene 17. Interaction with Max Perutz -- Scene 18. Working with Alan Coulson -- Scene 19. George Brownlee -- Scene 20. Brian Hartley and Aaron Klug -- Scene 21. Advice to young scientists -- Scene 22. Competition in science -- Scene 23. Mentoring young scientists -- Scene 24. Critical moments in research.


  • Creation: 2005-06-16


Conditions Governing Access

Portions of this collection have been digitized and are available online: Select tapes have been digitized thanks to support from CLIR Recordings at Risk Grant awarded in 2021, these tapes are available for research online via our Oral History Website and in person at CSHL Archives. Please contact CSHL Archives with any questions regarding availability.

Biographical / Historical

Frederick Sanger (August 13, 1918-November 19, 2013), OM, CH, CBE, FRS was an English biochemist and twice a Nobel laureate in chemistry. In 1958 he was awarded a Nobel prize in chemistry "for his work on the structure of proteins, especially that of insulin". In 1980, Walter Gilbert and Sanger shared half of the chemistry prize "for their contributions concerning the determination of base sequences in nucleic acids", also known as the "Sanger method" for DNA sequencing. The other half was awarded to Paul Berg "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA".

He is the fourth (and only living) person to have been awarded two Nobel Prizes, either wholly or in part.


1 Cassettes (Camcorder footage) : MiniDV - CSHL1147

1 Optical Disks (Talking science with Frederick Sanger) : DVD ; 38 min.

Language of Materials

From the Collection: English