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Amar Klar & Jeff Strathern, 2000-05-01

 Item — Multiple Containers
Oral History - Klar & Strathern
Oral History - Klar & Strathern

Scope and Contents

Amar Klar and Jeff Strathern, leading yeast geneticists, are interviewed by Mila Pollock at the National Cancer Institute, in Frederick, Maryland.

Amar Klar and Jeff Strathern discuss the following in their interview: Scene 1. Introduction -- Scene 2. Forming the Yeast Group at Cold Spring Harbor Laboratory -- Scene 3. Amar Klar arriving at Cold Spring Harbor Laboratory -- Scene 4. Experience working at Cold Spring Harbor Laboratory -- Scene 5. Jeff Strathern arriving at Cold Spring Harbor Laboratory -- Scene 6. Success in collaborative yeast research -- Scene 7. Changes at Cold Spring Harbor Laboratory -- Scene 8. Research on mating type switching -- Scene 9. Cold Spring Harbor Laboratory strengths -- Scene 10. Memories from Cold Spring Harbor Laboratory -- Scene 11. Family life at Cold Spring Harbor Laboratory -- Scene 12. Conversation with Jim Watson: Watson-Crick strands -- Scene 13. Current yeast research -- Scene 14. An important mating type experiment -- Scene 15. The Yeast Group at the National Cancer Institute Center for Cancer Research.

Dates

  • Creation: 2000-05-01

Creator

Conditions Governing Access

Portions of this collection have been digitized and are available online: https://library.cshl.edu/oralhistory/. Select tapes have been digitized thanks to support from CLIR Recordings at Risk Grant awarded in 2021, these tapes are available for research online via our Oral History Website and in person at CSHL Archives. Please contact CSHL Archives archives@cshl.edu with any questions regarding availability.

Biographical / Historical

Amar Klar (April 1, 1947-March 5, 2017) was a leading yeast geneticist and was concerned with the molecular biology of gene silencing and mating-type switching. Klar came from India to the University of Wisconsin in 1975 to receive his Ph.D. in bacteriology. From 1977 to 1984 he worked with Jeff Strathern and Jim Hicks in the Cold Spring Harbor Laboratory Yeast Group, studying the mechanism of mating type switching. Klar served as Director of the Delbrück Laboratory from 1985 to 1988. He left Cold Spring Harbor to join the ABL-Basic Research Program as Head of the Developmental Genetics Section. In 1999, Klar joined the National Cancer Institute-Center for Cancer Research and was a Principal Investigator in the Gene Regulation and Chromosome Biology Laboratory at National Cancer Institute-Center for Cancer Research.

Jeffrey Strathern, a leading yeast geneticist, obtained his Ph.D. from the Molecular Biology Institute at the University of Oregon in 1977. He then moved to Cold Spring Harbor Laboratory, where he became a senior staff member with the yeast genetics laboratory. In 1984, he joined the ABL-Basic Research Program at the National Cancer Institute (NCI) - Frederick Cancer Research and Development Center. His research remains centered on aspects of gene regulation and genetic recombination as revealed by studies in yeast. He was an NCI-Frederick Laboratory Chief, in the Gene Regulation and Chromosome Biology Laboratory (GRCBL), and Head, Genome Recombination and Regulation Section. Strathern worked together with Amar Klar and Jim Hicks in the Cold Spring Harbor Laboratory Yeast group from 1977 to 1984 where they made outstanding discoveries about the mechanism of mating type switching in yeast. He retired May 27, 2016 and now holds the title of scientist emeritus in the GRCBL at NCI.

Extent

2 Cassettes (Camcorder footage) : MiniDV - CSHL1090, CSHL1350 "Amar Klar & Jeff Strathern #3"

2 VHS : STRATHERN_KLAR_2000_01 [1:08:22] unedited; 2017 STRATHERN_KLAR_2000_02 [1:08:26] duplicate, unedited

1 Optical Disks (Talking science with Klar & Strathern) : DVD ; 63 min

2 Cassettes (Camcorder footage (assuming these are duplicates of MiniDV CSHL1090)) : Hi-8 - CSHL1306, CSHL1307

Language of Materials

From the Collection: English