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3'-end Cleavage, Polyadenylation, and Termination - James Manley


Scope and Contents

From the Series:

This meeting combined a historical perspective with updates on exciting developments and research directions of the current day. Speakers included pioneers in the field of mRNA-each of whom has made a great contribution to the field. The scientists presented their historic work from today's perspective, and then discussed it with the audience. In addition, an invited speaker covered the field from a historian's perspective. This meeting explored the first formulation and proof of the messenger RNA (mRNA) idea, and how further research over more than five decades has expanded and updated the fundamental concept. Speakers discussed discoveries associated with: negative and positive regulation of synthesis; function and turnover of mRNA in bacteria and archaea; fundamental discoveries in the context of the eukaryotic nucleus; current understanding of the regulation of mRNA synthesis and processing; and transport, longevity, and translation of mRNA in the eukaryotic cytoplasm. More than 140 scientists, graduate students, postdoctoral fellows, scholars, writers, journalists, and others attended the meeting. See


  • Creation: 2014



From the Series: 1 Gigabytes

Language of Materials

From the Collection: English

Repository Details

Part of the Cold Spring Harbor Laboratory Archives Repository

Library & Archives
Cold Spring Harbor Laboratory
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Cold Spring Harbor NY 11724 USA