Manley, James

Scope and Contents From the Series: This meeting combined a historical perspective with updates on exciting developments and research directions of the current day. Speakers included pioneers in the field of mRNA-each of whom has made a great contribution to the field. The scientists presented their historic work from today's perspective, and then discussed it with the audience. In addition, an invited speaker covered the field from a historian's perspective. This meeting explored the first formulation and proof of the...

Scope and Contents From the Series: The discovery of mRNA splicing in 1977 established a new step in the central dogma of molecular biology, the “flow” of genetic information from DNA to RNA to the protein product. Our meeting will focus on forty years of advances in this field with topics such as the spliceosome, alternative RNA splicing, diseases related to RNA splicing, and therapeutics focused on RNA splicing. The meeting will encompass discussions not only of what has already been accomplished, but also how this history...